Pharma Stocks

Reviewing Valuation After 46% Three-Month Share Price Surge

Centessa Pharmaceuticals (CNTA) stock has quietly gained steam over the past quarter, delivering a 46% climb in that time. Investors may be looking beyond short-term volatility and focusing on the company’s long-term pipeline prospects and recent momentum.

See our latest analysis for Centessa Pharmaceuticals.

Centessa’s latest share price of $22.86 reflects a remarkable run, with a 45.7% share price return over the past quarter in addition to a 44.6% total shareholder return in the last year. This momentum suggests investors are latching on to the company’s improving outlook and growing optimism around its R&D milestones.

If you’re curious about what other biotech and pharma stocks are making waves, now is a good time to explore See the full list for free.

But with shares up nearly 46% in just three months and a price target that still offers some upside, the question remains: is there real value left for new buyers, or has the market already priced in Centessa’s future growth?

Centessa Pharmaceuticals trades at a price-to-book ratio of 8.9x, which places it below its peer group average of 12.1x but well above the broader biotech industry’s average of just 2.6x. At its last close of $22.86, investors are valuing the company more highly than most other biotechs, though not quite as aggressively as direct peers.

The price-to-book ratio is commonly used for early-stage or unprofitable biotech firms because it reflects how much shareholders are willing to pay for each dollar of net assets. For companies still burning cash or investing heavily in R&D, markets often use this metric as a proxy for future potential breakthroughs, licensing deals, or acquisitions. In Centessa’s case, the current valuation could be signaling market expectations for its promising development pipeline and robust revenue growth forecasts, despite ongoing losses.

Despite the premium compared to the industry, Centessa trades at a discount to its immediate peers. The market appears to be betting that Centessa’s fast-paced revenue growth justifies this positioning, even as profitability remains out of reach for now. If the market’s view shifts on Centessa’s growth story, there is room for this multiple to move closer to or even overshoot either the peer average or wider biotech benchmarks.

See what the numbers say about this price — find out in our valuation breakdown.

Result: Price-to-Book Ratio of 8.9x (UNDERVALUED compared to peers, OVERVALUED compared to the industry)

However, ongoing losses and the uncertainty of clinical outcomes could quickly shift sentiment. This reminds investors that the biotech landscape remains unpredictable.

Find out about the key risks to this Centessa Pharmaceuticals narrative.

While the price-to-book ratio hints at undervaluation compared to peers, our DCF model takes a different perspective. According to this analysis, Centessa’s current $22.86 share price sits about 22% below its estimated fair value of $29.41. This suggests the stock could offer meaningful upside if long-term expectations are met. Still, is that optimism justified?

Look into how the SWS DCF model arrives at its fair value.

CNTA Discounted Cash Flow as at Oct 2025

Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Centessa Pharmaceuticals for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match – so you never miss a potential opportunity.

If you have your own take on Centessa Pharmaceuticals or want to dive deeper into the numbers, you can build a personalized narrative in just a few minutes. Do it your way

A great starting point for your Centessa Pharmaceuticals research is our analysis highlighting 3 key rewards and 1 important warning sign that could impact your investment decision.

Don’t limit yourself to just one stock when the market is bursting with opportunities. Expand your outlook and stay ahead with these targeted strategies:

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Companies discussed in this article include CNTA.

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button