Pharma Stocks

Alnylam Pharmaceuticals (ALNY): Evaluating Valuation After FDA Tightens Drug Advertising Disclosure Rules

Regulatory shakeups rarely go unnoticed on Wall Street, and the FDA’s latest crackdown on direct-to-consumer drug ads has certainly put Alnylam Pharmaceuticals (ALNY) in the spotlight. The agency’s stricter rules, requiring firms to fully list all drug side effects in every advertisement, directly impact how Alnylam communicates about its therapies. For investors, the question is whether this change is just a new cost of doing business or something that could reshape the company’s risk profile and growth strategy.

Despite the heightened scrutiny, share price action over the past year suggests the market remains optimistic about Alnylam’s long-term outlook. The company has kept momentum on its side, with strong returns not only year-to-date, but stretching across the past year and even longer horizons. In addition, Alnylam recently joined the Alliance for Genomic Discovery and has been active with new clinical partnerships and conference presentations, making clear that its innovation engine is still running.

After an eventful stretch and a run-up in the stock, investors are left to wonder whether Alnylam is now a bargain or if the market is already factoring in its next stage of growth.

Most Popular Narrative: 2.6% Overvalued

Based on the most widely followed narrative, Alnylam Pharmaceuticals is currently seen as slightly overvalued, with the stock trading just above the average analyst price target derived from robust revenue and profit forecasts.

The analysts have a consensus price target of $426.26 for Alnylam Pharmaceuticals based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $583.0, and the most bearish reporting a price target of just $236.0.

Want to know what is fueling this ambitious valuation? Analyst models are banking on dramatic financial growth and bold profit milestones; numbers that could redefine Alnylam’s standing in biotech. The real surprise? Underneath the consensus target, there are some eye-opening growth assumptions that you will want to see for yourself.

Result: Fair Value of $447.15 (OVERVALUED)

Have a read of the narrative in full and understand what’s behind the forecasts.

However, ongoing pressure on drug pricing and Alnylam’s heavy reliance on its TTR franchise could quickly challenge expectations for uninterrupted double-digit growth.

Find out about the key risks to this Alnylam Pharmaceuticals narrative.

Another View: Deep Value or a Warning Sign?

Taking a different approach, our SWS DCF model arrives at a dramatically more optimistic valuation. This suggests Alnylam may be trading well below its fair value. So, which outlook should investors trust for the road ahead?

Look into how the SWS DCF model arrives at its fair value.

ALNY Discounted Cash Flow as at Sep 2025

Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Alnylam Pharmaceuticals for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match – so you never miss a potential opportunity.

Build Your Own Alnylam Pharmaceuticals Narrative

If you want to dig into the numbers yourself or craft your own perspective on Alnylam Pharmaceuticals, you can do so quickly and easily. Do it your way.

A great starting point for your Alnylam Pharmaceuticals research is our analysis highlighting 2 key rewards and 1 important warning sign that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data
and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice.
It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your
financial situation. We aim to bring you long-term focused analysis driven by fundamental data.
Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.
Simply Wall St has no position in any stocks mentioned.

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